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George Wang and Yibei Jiang Published a Paper

  • Writer: QCB at USC
    QCB at USC
  • Oct 1
  • 1 min read

CBB graduate students George Wang (top left) and Yibei Jiang (top right), as co-first authors from Dr. Remo Rohs’s (bottom) lab, with contributions from Dr. Oscar Aparicio's (center left) and Dr. Vadim Cherezov's (center right) groups, published a paper titled “Novel fold and wing structure of Forkhead transcription factor facilitate DNA binding” in Nucleic Acids Research. The study reveals a novel protein fold with base-specific interactions in the DNA minor groove. Molecular dynamics simulations related Fkh1 function to conformational flexibility of protein wing residues. Please read the paper here. The coordinates of the new structure were deposited in the Protein Data Bank under PDB accession code 9EFW.


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