Obadiah Mulder Published a Paper

CBB Ph.D. student Obadiah Mulder (left) from Dr. Doc Edge’s (right) lab published a paper titled “An agent-based model of metabolic signaling oscillations in Bacillus subtilis biofilms” in PLoS Computational Biology. The authors built an agent-based model of nutrient consumption and flow in a bacterial biofilm that reproduces oscillatory signaling behavior observed in in vitro Bacillus subtilis biofilms. The model shows how an apparent collective, coordinated behavior can emerge from individual cells' behavior. This work was in collaboration with Dr. Joe Larkin of Boston University, whose lab provided new observations of B. subtilis behavior consistent with the model. Please read the paper here.