Anupam Dey from Dr. MacLean’s Lab Published a Paper

QCB postdoc Anupam Dey (left) from Dr. MacLean’s (right) lab published a paper “Transition paths across the epithelial-mesenchymal transition landscape are dictated by network logic” in the journal Development. The study investigates the role of logic in gene regulatory network (GRN) models. The study revealed that the choice of network logic (AND vs OR) profoundly impacts cell fate, highlighting the caution that ought to be exercised in constructing models, and enabling prediction of experimental designs sufficient to infer the logic of GRNs in live cells. Please read the paper here.