The lab of QCB joint faculty Dr. Cornelius Gati published a breakthrough paper in Cell titled “Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors”. The study reveals 9 cryo-EM structures of the key immune system receptors C5aR1 and C3aR in complex with different G proteins and ligands, explaining their biological and pathological mechanisms. This paper can be found here, and Dornsife press coverage here.
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