Dr. Geoff Fudenberg’s (right) lab had two papers published in PLoS Computational biology in collaboration with the Open2C team. The first, with contributions from QCB student Yao Xiao (left), "Cooltools: Enabling high-resolution Hi-C analysis in Python", enables analysis of large sparse 3D genome folding datasets in Python and through the command line (Full article here). The second paper, "Pairtools: From sequencing data to chromosome contacts", discusses a flexible suite of high-performance tools for contact extraction from large-scale sequencing data. (Full article here).
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