NEWS

QCB postdocs Drs. Woojin Lee (top left) and Jordy Homing Lam (top right) from Dr. Katritch’s lab (bottom left), in collaboration with Dr. Cherezov's lab (bottom right) in the Chemistry Department, published a paper titled “Structural insights into the mechanism of activation and inhibition of the prostaglandin D2 receptor 1” in Nature Communications . The study discovered a new functional mechanism in GPCRs, using a combination of cryo-EM and extensive molecular dynamics char

QCB postdoc Dr. Priscilla Chan from Dr. Steve A. Kay’s lab was awarded the prestigious John H. Richardson Endowed Postdoctoral Fellowship to support her postdoctoral research project on investigating the effects of circadian clock compounds on the glioblastoma tumor microenvironment and synergy with chemoradiation. Dr. Chan gave a poster presentation to the Achievement Rewards for Collegiate Scientists (ARCS) Foundation members at the annual luncheon at the California Club on

QCB joint faculty Peter (Yingxiao) Wang published a paper titled “Tumour priming by ultrasound mechanogenetics for CAR T therapy” in Nature Materials . Please read the paper here and the Viterbi School of Engineering press release here .

The QCB department congratulates our wonderful Administrative Assistant, Tanya Moore, now Tanya McReynolds, and her husband on their recent marriage. We wish them many happy years together and thank Tanya for everything she does for QCB.

CBB Ph.D. student Walfred Ma (left) from Dr. Mark Chaisson's group (right) published a paper in Nature Genetics titled “Genotyping sequence-resolved copy number variation using pangenomes reveals paralog-specific global diversity and expression divergence of duplicated genes”. The study describes a new approach, ctyper, which links short read sequencing data in biobanks to complex variation resolved in human pangenome assemblies. This method improves genotyping for biomedica

CBB Ph.D. student Yibei Jiang (Rohs lab) successfully defended her dissertation "Understanding the Structural Basis Transcription Factor-DNA Binding through Molecular Dynamics" and joined Illumina, Inc. in San Diego.

QCB joint faculty Dr. Paul Thompson led a paper titled “Classification of major depressive disorder using vertex-wise brain sulcal depth, curvature, and thickness with a deep and a shallow learning model.”, published in Molecular Psychiatry . Please read the paper here .

The Quantitative Biology Association's president, Karen Lee, and vice president, Richard Zhang (both pictured), along with QCB department chair Dr. Remo Rohs, spoke to parents of current and prospective QBIO students at Trojan Family Weekend.

QCB joint faculty Dr. Cornelius Gati published a paper titled “Structural snapshots capture nucleotide release at the μ-opioid receptor” in Nature . Please read the paper here .

QBIO graduate Samantha Graham defended her dissertation at the University of Minnesota. Her Ph.D. advisor was Dr. Ran Blekhman from the University of Chicago. Samantha, who was in the first cohort of QBIO students, is now a postdoc at Brigham and Women's Hospital in Boston.

QCB joint faculty Dr. Kate White published a paper titled “Secretory stimuli distinctly regulate insulin secretory granule maturation through structural remodeling” in Structure . Please read the paper here .

QCB faculty Adam MacLean (top left) and a former CBB Ph.D. student Megan Rommelfanger (top right, now a research scientist at Altos Labs) published a paper in iScience titled “Gene regulatory network inference with popInfer reveals dynamic regulation of hematopoietic stem cell quiescence”. The method, popinfer, developed in this study, was used to discover a network of gene regulation that controls quiescence in blood stem cells, potentially contributing to healthier aging p